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colgate duraphat toothpaste 5000pm 51g
  • High-strength fluoride
  • Protects against cavities

Colgate Duraphat Toothpaste 5000pm

£12.4951g toothpasteIn stock
Pricing
Pack One-off
51g toothpaste £12.49
2 × 51g toothpaste £23.49
3 × 51g toothpaste £30.99
Start oral care assessment

Prescription medicines are only supplied if a prescriber approves them after your oral care assessment.

  1. You answer a few questions.Two to three minutes, no appointment.
  2. A prescriber reviews your answers.The same day for orders before 3pm.
  3. We dispense and post it.In plain packaging.

Order in the next

16h 8m 29s

10th October 2026

Works
Strengthens enamelHigh-fluoride
Used
3x dailyBrush as toothpaste
Suitable for
Age 16+High decay risk
Form
Toothpaste5000ppm
From
£12.49
Dispatched
Same dayon working days before 3pm
HOW IT WORKS
High-fluoride toothpaste strengthens enamel
WARNING
Spit out; do not swallow
PRESCRIPTION
Price includes our prescription service

What is Colgate Duraphat?

Colgate Duraphat 5000ppm is a high-strength fluoride toothpaste prescribed for the prevention of dental caries (tooth decay) in adults and adolescents aged 16 years and over who are at increased risk. It contains 5000 parts per million (ppm) of fluoride - over three times more than regular toothpaste - to strengthen enamel, prevent cavities, and stop early decay in its tracks.

How does it work?

Fluoride helps remineralise weakened enamel and makes teeth more resistant to acid attacks from bacteria and sugary foods. Duraphat's high fluoride content is especially effective for people who have a history of dental decay, wear braces or dentures, suffer from dry mouth, or have exposed root surfaces. It helps to reduce bacterial acid production and promotes repair of early tooth damage before cavities form.

How to use Colgate Duraphat

  • Brush your teeth three times daily, ideally after meals
  • Use a 2 cm ribbon on your toothbrush and brush for three minutes
  • Spit out after brushing - do not rinse, so the fluoride stays on your teeth
  • Do not swallow the toothpaste
  • Not recommended for use in children under 16 years

Who is it for?

Colgate Duraphat is designed for people at high risk of dental decay, including:

  • Frequent cavities or history of decay
  • Orthodontic appliances (braces, retainers)
  • Dry mouth (xerostomia) or reduced saliva flow
  • Exposed tooth roots or gum recession
  • People with crowns, bridges, or dentures

Side effects

Colgate Duraphat is generally well tolerated. Possible side effects include:

  • Mild irritation of the gums or mouth
  • Allergic reaction (rare)
  • Dental fluorosis (if swallowed regularly over time)

Always follow the directions provided and consult your dentist or pharmacist if unsure.

Warnings and precautions

Colgate Duraphat 5000 is a prescription-only medicine and should be used only under the supervision of a dentist or prescribing pharmacist. Important warnings include:

  • Do not use in children or adolescents under 16 years of age
  • Do not swallow - the high fluoride content can be harmful if ingested regularly
  • Do not use other fluoride products (e.g. mouthwash or supplements)
  • Use only the recommended amount - applying too much does not improve effectiveness
  • Not suitable for people with fluoride allergy or intolerance

If you experience unusual symptoms, such as stomach upset or white spots on your teeth (dental fluorosis), stop use and seek medical advice.

Frequently Asked Questions

  • Why is Colgate Duraphat only available on prescription?

    Due to its high fluoride content, Duraphat is classed as a prescription-only medicine in the UK.

  • Can I use Duraphat instead of my normal toothpaste?

    Yes, it replaces your standard toothpaste during treatment. Use it exactly as advised and avoid using other fluoride products at the same time unless directed.

  • Is Duraphat safe for long-term use?

    Yes, many patients use Duraphat long term under dental supervision. Regular reviews with your dentist or prescriber help ensure continued safe use.

  • What if I accidentally swallow some?

    Swallowing a small amount by accident is unlikely to cause harm, but frequent swallowing can lead to side effects like fluorosis. Always spit after brushing.

Reviews describe individual experiences of our pharmacy service and are not a guide to how a medicine will work for you. Reviews are collected and verified by Priorly and are published unedited. Suspected side effects should be reported through the MHRA Yellow Card scheme.

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