Night Nurse Capsules

What it is

Night Nurse Capsules are an over-the-counter cold and flu medicine designed for night-time use. They contain paracetamol, promethazine, and dextromethorphan to help relieve multiple symptoms while helping you get a restful night's sleep.

How it works

Each capsule contains three active ingredients that target different symptoms. Paracetamol helps reduce fever and relieve aches or pain. Promethazine, an antihistamine, helps dry a runny nose and aids sleep. Dextromethorphan is a cough suppressant that helps reduce persistent or irritating coughs.

How to use

Adults and children aged 16 years and over should take two capsules just before bedtime with a glass of water. Do not take more than two capsules in 24 hours. Avoid taking other paracetamol-containing medicines at the same time. If symptoms persist after three days, seek advice from a pharmacist or doctor.

Who it's for

Night Nurse Capsules are suitable for adults and teenagers aged 16 years and above who need relief from cold and flu symptoms at night, such as a blocked or runny nose, cough, sore throat, headache, fever, or aches and pains.

When should these capsules not be used?

Do not use Night Nurse Capsules if you:

• Are under 16 years of age
• Are pregnant or breastfeeding
• Have heart, liver or kidney problems
• Are taking other medicines that contain paracetamol or cough suppressants
• Have taken a monoamine oxidase inhibitor (MAOI) antidepressant in the last 14 days
• Have glaucoma, asthma, or prostate enlargement
• Are taking sedatives or tranquillisers
• Are allergic to paracetamol, promethazine, or dextromethorphan

Drowsiness and driving

Night Nurse Capsules can cause drowsiness due to the antihistamine promethazine. This effect may last into the following morning. Do not drive, cycle, or operate machinery after taking Night Nurse or if you still feel drowsy. Avoid drinking alcohol, as it can increase sleepiness and reduce alertness.

Common interactions

Night Nurse may interact with antidepressants (such as MAOIs), sedatives, tranquillisers, or other cough and cold medicines. Do not use within 14 days of taking an MAOI antidepressant. Speak to your pharmacist or GP before use if you take regular medication.

Pregnancy/Breastfeeding

Night Nurse Capsules are not recommended during pregnancy or breastfeeding. If you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor or pharmacist before taking this medicine.

Possible side effects

Like all medicines, Night Nurse Capsules can cause side effects, although not everyone gets them.
Common side effects include:

• Feeling sleepy or drowsy
• Dizziness
• Dry mouth
• Blurred vision
• Constipation

Less common effects may include:

• Nausea
• Confusion or hallucinations especially in older adults
• Stomach upset

Stop taking the capsules and seek medical help immediately if you experience:

• Allergic reactions such as rash, swelling, or difficulty breathing.
• Severe dizziness or fainting
• Irregular heartbeat
• Severe stomach pain
• Difficulty passing urine
• Skin rash, peeling, mouth ulcers

More information

For more information on Night Nurse and its ingredients please visit:
NHS - Promethazine
Night nurse (SPC).