Mounjaro Pen 2.5mg

What is Mounjaro?

Mounjaro (also known by its generic name tirzepatide) is an MHRA approved medicine that can be used to improve blood sugar (glucose) levels in adults with type 2 diabetes mellitus. It is also licensed for the use of weight loss, with a significant reduction in body weight when using Mounjaro over 72 weeks. The active ingredient in Mounjaro (tirzepatide) works by activating two receptors: the glucose-dependent insulinotropic polypeptide (GIP) receptors and the glucagon-like peptide-1 (GLP-1) receptors. These natural hormones help regulate blood sugar levels by assisting the pancreas in producing more insulin, reducing liver sugar production, and slowing down the rate at which food passes through the body, leading to a feeling of fullness.

How it works

Mounjaro (generic name tirzepatide) binds to and activates two receptors in your body glucose-dependent insulinotropic polypeptide (GIP) receptors and glucagon-like peptide-1 (GLP-1) receptors.
GLP-1 (Glucagon-like peptide-1): This hormone is naturally released from your digestive tract. It helps lower blood sugar levels and promotes a feeling of fullness.
GIP (Glucose-dependent insulinotropic polypeptide): GIP stimulates the release of insulin.
By causing increased levels of these hormones in your body, Mounjaro alters how your body reacts to food. Mounjaro activates special areas in the brain that make you feel full, as well as slowing the rate at which food passes through your body (gastric emptying) as a result, you feel fuller more quickly and for longer, reducing your apetite making it easier for you eat less and lose weight.

How to buy Mounjaro online

You can arrange a consultation with our prescriber to buy Mounjaro online in the UK. We are a regulated GPhC registered pharmacy based in the UK and offer free next day delivery with your Mounjaro order. After a short or long call (depending on your needs) with the prescriber your order will be shipped out for delivery on a day you choose. As this item is a 'Prescription Only Medication' (POM) a prescriber needs to have a consultation to make sure treatment is appropriate before you can purchase this medication. Be aware of anywhere offering to sell this item without a prior consultation as it is likely a website operating illegaly and could be selling fake or counterfeit medicine.

How to use a Mounjaro injection pen

1. Inspect the pen, do not use the pen if the medication is expired, has been frozen, contains particles, appears cloudy, or has an unusual color (Mounjaro should be colorless to slightly yellow).
2. Wash your hands and choose and clean your injection site making sure it is dry before injecting. You can inject Mounjaro into your: Stomach, thigh or upper arm.
3. Pull the cap off the pen and get a new pen needle, you should always make sure to select a new needle for each injection to prevent infections and injuries caused by blunt needles.
4. Push the capped needle onto the pen and twist until tight.
5. Remove the outer needle shield and keep it to one side for later use.
6. Remove the inner needle shield and dispose of it.
7. Prime the pen: Slowly turn the dose knob until you hear two clicks, and the extended line is shown in the dose window.
8. Hold your pen with the needle pointing up and tap the pen gently until the air bubbles rise to the top.
9. Press down on the dose button and hold for 5 seconds until the [0] is shown in the dose window. Do not inject the prime dose.
10. Priming removes air from the cartridge and makes sure that your pen is working correctly. Your pen has been primed if a small amount of medicine comes out of the tip of the pen needle.
11. You are now ready to inject, turn the knob until [1] is shown in the dose window. This is equal to a full 0.6ml dose.
12. Insert the needle into your skin and push down on the dose button until it stops and hold for 5 seconds.
13. Make sure [0] is shown in the dose window.
14. If [0] is shown you can remove the needle. If it is not shown push back down on the button do not redial the dose.
15. Pull the needle out of your skin. A drop of medicine on the needle tip is normal. It will not affect your dose.
16. Take off the needle and dispose of in your sharps bin and replace the pen cap

If you need any help at all with how to inject, do not hesitate to ask the prescriber.

Mounjaro dosing guide

Mounjaro comes in a variety of different strengths and to help keep side effects to a minumum you will be initiated on 2.5mg and titrated up by 2.5mg every 4 weeks.

It is important to note you do not have to move up every 4 weeks and you can move back down to a lower strength if you cannot tolerate the higher strength. You should only move up to the next strength if you are tolerating the current stength with no side effects.

Who cannot use Mounjaro

It is generally well tolerated and suitable for most adults. However it may not be suitable if you:

1. Have previously had an allergic reaction to Mounjaro
2. Have a history of pancreatitis
3. Have liver problems
4. Currently taking blood thinners such as Warfarin
5. Have GI problems such as chronic constipation
6. Have thyroid problems
7. Have kidney problems
8. Currently taking immunosuppressants

Is Mounjaro safe?

It has been licensed by the MHRA and the FDA. It can cause side effects like any medication but usually these are well tolerated and decrease with use.

Mounjaro and oral contraceptives

Mounjaro can alter hormone levels we recommend you use other forms of contraceptive such as barrier (condoms) or the coil while taking Mounjaro.

Mounjaro and pregnancy

If you are thinking of becoming or are currently pregnant, it is not recommended you start or continue using Mounjaro as there is no data on the safety of Mounjaro during pregnancy. We advise you stop taking Mounjaro 6-8 weeks prior to trying to conceive.

Mounjaro and breastfeeding

If you are breatfeeding, it is not recommended you start or continue using Mounjaro as there is no data on the safety of Mounjaro during breastfeeding.

Help with nausea

A common side effect of Mounjaro is nausea, usually your side effects will get better as you get used to your medication but you can take a few steps to help:

1. Make sure you get plenty of fresh air
2. Take regular sips of a cold drink
3. Drink peppermint tea
4. Eat foods or drink, drinks containing giner
5. Eat smaller meals
6. Eat slower
7. Eat light, bland foods (such as saltine crackers or plain bread).

You should avoid:

1. Cooking strong-smelling food
2. Greasy or fried food
3. Eating quickly
4. Large meals
5. Lieing down after eating
6. Clothes that are tight against your waist or stomach

Medicine such as Cyclizine is a popular choice and can help as you get used to the medication.

Mounjaro side effects

Mounjaro is generally well tolerated in most adults but as with all medication it can have side effects some of the more common side effects include:

1. Feeling sick (nausea)
2. Diarrhoea
3. Being sick (vomiting)
4. Constipation
5. Injection site reactions
6. Indigestion (dyspepsia)
7. Gas (flatulence)
8. Acid reflux or heartburn

Usually any side effects are not severe and will go away after you get used to the medication.
Some more rarer side effects include:

1. Low blood sugar
2. Gallstones
3. Inflamed pancreas
4. It is not known if Mounjaro will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. Do not take Mounjaro if you or any of your family have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

It is important to note Mounjaro has very small risk of pancreatitis, if you experience suddenly getting severe pain in the upper part of your abdomen that spreads to your back, feeling or being sick, a high temperature of 38C or more (fever), seek a doctor immediately.

Mounjaro interactions

It has minimal interactions the main ones to watch out for are:

1. Other medications that can lower your blood sugar levels
2. Oral contraceptives
3. Warfarin - Tirzepatide might affect the absorption of Warfarin

You should also be aware that any herbal or alternative remedies you take may also interact with this medication and cause side effects. If you are taking any herbal or alternative remedies make sure to mention them to the prescriber, so we can make sure they are safe to take together.
For a full list of interactions see: Mounjaro interactions.

Mounjaro Alternatives

There are other alternatives to Mounjaro:

• Wegovy
• We also offer an oral solution for weight loss in certain circumstances, if you would like to try this please book a consultation with our prescriber to discuss your options.

More Mounjaro information

If you would like more information you can find the SPC: Mounjaro SPC